Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Neriifolin 90 LC/MS ELSD1MG
Neriifolin is a cardenolide glycoside found in the seeds of Cerbera odollam and in Thevetia ahouia and Thevitia neriifolia.
Cayman Chemical SynthetIc GItoxIn 10mg
A cardiac glycoside with cardiotonic and antiarrhythmic activities; inhibits Na+/K+-ATPase in an isoform-specific biphasic manner with IC50 values of 0.298 and 410 µM for the high- and low affinity human erythrocyte isoenzymes, respectively, and 1.18 and 28.5 µM for the high- and low affinity porcine cerebral cortex isoenzymes, respectively; increases contractility and rhythmicity in isolated guinea pig heart in a concentration-dependent manner; a degradation product of digoxin
eMolecules 404-86-4 | Capsaicin, natural | Chem-Impex305.418 | C18H27NO3 | 100.000 | COc1cc(CNC(=O)CCCCC=CC(C)C)ccc1O | 1g | 112756073
Capsaicin, natural | Chem-Impex | 404-86-4305.418 | C18H27NO3 | 100.000 | COc1cc(CNC(=O)CCCCC=CC(C)C)ccc1O | 1g | 112756073
U.S. Pharmacopeia Ketorolac Related Compound C, 113502-52-6, MFCD22048820, 20 mg
Empirical Formula (Hill Notation): C14H11NO2, Molecular Weight: 225.24, Synonym: 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one.
Apexbio Technology LLC (-)-epicatechin gallate 1257-08-5 10mM (in 1mL DMSO)
(-)-Epicatechin gallate (ECG) is a catechin compound abundant in green tea displaying bioactivity to modulate cell proliferation apoptosis and gene expression pathways In colon HCT-116 cells ECG induces apoptosis through activating transcription factor 3 (ATF3) regulated via activation of early growth response protein 1 (EGR-1) In these cancer cells ECG upregulates apoptotic factor NAG-1 and increases caspase-3 activity at concentrations around 150 M ECG s cytotoxic potency differs among cell types with an NR50 (midpoint cytotoxic concentration) of approximately 67 M in HSC-2 oral cancer cells while normal human fibroblast HGF-2 cells show greater resistance with an NR50 near 100 M ECG metabolites identified in rat urine include various O-methylated derivatives useful as biomarkers for metabolism studies ECG serves as a research tool for oncology mechanisms and apoptosis signaling pathways
Medchemexpress LLC Flunixin (meglumine) | 42461-84-7 | 99.65% | 1 ML
Flunixin meglumine is a cyclooxygenase (COX) inhibitor exhibiting anti-inflammatory effects. It inhibits lipopolysaccharide-induced inducible nitric oxide synthase (iNOS) activity and nuclear factor kappa B (NfκB) activation in RAW 264.7 murine macrophages. In vivo, it inhibits carrageenan-induced exudate PGE2 and serum TXB2 generation.
Medchemexpress LLC Metformin-d6 hydrochloride | 1185166-01-1 | MFCD06658649 | 98.0% | 171.66 g/mol | C4H6D6ClN5 | 5 MG
Metformin-d6 hydrochloride is a deuterium-labeled metformin hydrochloride supplied as a research-grade analytical standard for use as an internal standard in quantitative LC-MS/GC-MS and tracer studies. For laboratory research use only; not for human consumption.
- Deuterium-labeled analogue suitable as an internal standard for mass spectrometry.
- High chemical purity: 98.0% as reported by supplier certificate of analysis.
- High isotopic enrichment (99.8%), supporting accurate quantification and tracing.
- Available as a solid in small analytical quantities for method development and validation.
- Compatible with common analytical workflows including LC-MS and GC-MS.
Medchemexpress LLC Hydrochlorothiazide (standard) | 58-93-5 | 99.6% | 50 MG
Hydrochlorothiazide (Standard) is the analytical standard of Hydrochlorothiazide, intended for research and analytical applications. It is an orally active diuretic agent of the thiazide class that inhibits the transforming TGF-β/Smad signaling pathway. It also has direct vascular relaxant effects by opening the calcium-activated potassium (KCA) channel, improving cardiac function, reducing fibrosis, and exhibiting an antihypertensive effect. This compound is an analytical standard supplied for assay.
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Idelalisib-d5 | 1830330-31-8 | 98.4% | 1 MG
Idelalisib-d5 is a deuterium-labeled Idelalisib. It is a highly selective and orally bioavailable p110δ inhibitor.
- Serves as a tracer
- Functions as an internal standard for quantitative analysis
- Compatible with NMR, GC-MS, or LC-MS techniques
Medchemexpress LLC Tofacitinib impurity 4 | 384338-23-2 | 96.0% | 218.34 | 50 MG
Tofacitinib impurity 4 is an impurity of Tofacitinib. This product is designed for research use only.
- Appearance: Liquid
- Color: Colorless to light yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Pure form can be stored at -20°C for 3 years or 4°C for 2 years; in solvent, it can be stored at -80°C for 6 months or -20°C for 1 month
Apexbio Technology LLC Ciprofloxacin (hydrochloride)(Synonyms: Cipro, Ciprofloxacin HCl, Ciprofloxacine hydrochloride, Ciprofloxacin hydrochloride monohydrate), 5g, CAS: 93107-08-5.
Ciprofloxacin (hydrochloride) (CAS 93107-08-5) is a fluoroquinolone antibiotic targeting bacterial DNA gyrase and topoisomerase IV enzymes essential for bacterial DNA replication and supercoiling By inhibiting these enzymes ciprofloxacin prevents bacterial chromosome replication and proliferation It also displays immunomodulatory activity evidenced by reduced serum pro-inflammatory cytokines (IL-6 KC) and decreased apoptosis and autophagy in radiation-induced injury mouse models Ciprofloxacin is FDA-approved for treating inhalational anthrax exposure significantly enhancing survival in rhesus monkeys infected with aerosolized B anthracis
Medchemexpress LLC Ganoderic acid C2 | 103773-62-2 | 518.68 | 1 ML
Ganoderic acid C2 is a bioactive triterpenoid found in *Ganoderma lucidum*. It possesses potential anti-tumor bioactivity, antihistamine, anti-aging, and cytotoxic effects. It is an inhibitor for aldose reductase with an IC50 of 43.8 μM.
- Purity: 99.72%
- Bioactive triterpenoid found in *Ganoderma lucidum*
- Potential activities include anti-tumor, antihistamine, anti-aging, and cytotoxic effects
- Aldose reductase inhibitor with an IC50 of 43.8 μM
- Appearance: solid, white to off-white
- Immunomodulatory activity exhibited in Cyclophosphamide-induced immunosuppression mouse models
![Medchemexpress LLC 4H-imidazo[1,5-a]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo- | 84378-44-9 | 100.0% | 275.24 | C13H10FN3O3 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000229210.png-250.jpg)
Medchemexpress LLC 4H-imidazo[1,5-a]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo- | 84378-44-9 | 100.0% | 275.24 | C13H10FN3O3 | 1 ML
Flumazenil acid is the carboxylic acid metabolite of flumazenil, provided as a high-purity reference material for research on GABAA receptor pharmacology and drug metabolism. It is supplied as a powder and is commonly prepared as a 10 mM solution (1 mL) for in vitro studies.
- High purity: 99.96% as reported by certificate of analysis.
- Molecular formula C13H10FN3O3 and molecular weight 275.24 g/mol.
- Available as powder; solutions commonly prepared at 10 mM, 1 mL volumes.
- Storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (6 months) or -20 °C (1 month).
- Intended for research use in pharmacology and metabolism studies (in vitro).
Medchemexpress LLC Berberine hemisulfate | 316-41-6 | 384.40 | 1 G
Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. This compound demonstrates anti-inflammatory, antibiobic, antitumor, cardiovascular protective, and neuroprotective activities, and is intended for research use only.
- Exhibits antimicrobial activity by inhibiting cell division protein FtsZ or through DNA/RNA binding.
- Shows anti-inflammatory activity by inhibiting TNF-α and its downstream pathways AP-1 and NF-kB.
- Provides neuroprotective efficacy by inhibiting reactive oxygen species (ROS) production and caspase activation.
- Attenuates metabolic diseases by regulating lipid composition and inhibiting insulin resistance.
Medchemexpress LLC Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) | 25 MG
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) is an antibiotic characterized by good oral absorption and broad-spectrum antimicrobial activity. It functions by inhibiting the biosynthesis of polypeptides in the cell wall, thereby hindering cell growth.
- Good oral absorption
- Broad-spectrum antimicrobial activity
- Inhibits biosynthesis of polypeptides in the cell wall
- Inhibits cell growth
- For research use only